| Item Type | Name |
|
Concept
|
Actins
|
|
Concept
|
Action Potentials
|
|
Concept
|
Adenosine
|
|
Concept
|
Aortic Coarctation
|
|
Concept
|
Aortic Valve Stenosis
|
|
Concept
|
Abnormalities, Multiple
|
|
Concept
|
Blood Flow Velocity
|
|
Concept
|
Cardiomyopathy, Hypertrophic
|
|
Concept
|
Anal Canal
|
|
Concept
|
Aortic Valve
|
|
Concept
|
Cleft Lip
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Cell Movement
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Atrial Fibrillation
|
|
Concept
|
Atrioventricular Node
|
|
Concept
|
Binding Sites
|
|
Concept
|
Blastomeres
|
|
Concept
|
Biopsy
|
|
Concept
|
Brain
|
|
Concept
|
Embryonic Induction
|
|
Concept
|
Chromosomes, Human, Pair 1
|
|
Concept
|
Cardiomyopathy, Dilated
|
|
Concept
|
Cell Cycle
|
|
Concept
|
Chromosome Deletion
|
|
Concept
|
Cleft Palate
|
|
Concept
|
Coronary Artery Disease
|
|
Concept
|
Diffusion of Innovation
|
|
Concept
|
Down Syndrome
|
|
Concept
|
Cell Fusion
|
|
Concept
|
Echocardiography
|
|
Concept
|
Ductus Arteriosus, Patent
|
|
Concept
|
Electrophysiology
|
|
Concept
|
Cilia
|
|
Concept
|
DNA, Superhelical
|
|
Concept
|
Mice, Inbred C3H
|
|
Concept
|
DNA (Cytosine-5-)-Methyltransferases
|
|
Concept
|
Heart Septal Defects, Atrial
|
|
Concept
|
Hematopoietic Stem Cells
|
|
Concept
|
Escherichia coli
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Purpura, Thrombocytopenic
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Middle Aged
|
|
Concept
|
Repetitive Sequences, Nucleic Acid
|
|
Concept
|
Nucleic Acid Conformation
|
|
Concept
|
Mediastinal Neoplasms
|
|
Concept
|
Embryonic and Fetal Development
|
|
Concept
|
Periodicity
|
|
Concept
|
Pre-Excitation Syndromes
|
|
Concept
|
Procainamide
|
|
Concept
|
Tetralogy of Fallot
|
|
Concept
|
Protein Binding
|
|
Concept
|
Genetic Markers
|
|
Concept
|
Heart Defects, Congenital
|
|
Concept
|
Heart Septal Defects, Ventricular
|
|
Concept
|
Wolff-Parkinson-White Syndrome
|
|
Concept
|
Xenopus
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Sarcomeres
|
|
Concept
|
RNA Splicing
|
|
Concept
|
Humans
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
United States
|
|
Concept
|
Trisomy
|
|
Concept
|
Tamoxifen
|
|
Concept
|
Xenopus laevis
|
|
Concept
|
Biomarkers
|
|
Concept
|
Sodium Channels
|
|
Concept
|
Chromosomes, Artificial, Bacterial
|
|
Concept
|
Vacuolar Proton-Translocating ATPases
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Chromosomes, Mammalian
|
|
Concept
|
Lower Extremity Deformities, Congenital
|
|
Concept
|
Limb Deformities, Congenital
|
|
Concept
|
RNA-Binding Proteins
|
|
Concept
|
Hypertrophy, Left Ventricular
|
|
Concept
|
Apoptosis
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Basic-Leucine Zipper Transcription Factors
|
|
Concept
|
Chemokines, CC
|
|
Concept
|
Protein Transport
|
|
Concept
|
Cardiomyopathy, Hypertrophic, Familial
|
|
Concept
|
Calcium Signaling
|
|
Concept
|
Myosin Heavy Chains
|
|
Concept
|
Exome
|
|
Concept
|
Peripheral Blood Stem Cell Transplantation
|
|
Concept
|
Embryonic Development
|
|
Concept
|
Smad4 Protein
|
|
Concept
|
Response Elements
|
|
Concept
|
Active Transport, Cell Nucleus
|
|
Concept
|
Retinal Dehydrogenase
|
|
Concept
|
Platelet Count
|
|
Concept
|
Animals, Genetically Modified
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Mice
|
|
Concept
|
Sarcoplasmic Reticulum
|
|
Concept
|
Laser Therapy
|
|
Concept
|
Brugada Syndrome
|
|
Concept
|
Mechanotransduction, Cellular
|
|
Concept
|
HEK293 Cells
|
|
Concept
|
Substrate Specificity
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Insulin-Secreting Cells
|
|
Concept
|
Regulatory Elements, Transcriptional
|
|
Concept
|
Chemokine CCL4
|
|
Concept
|
Zebrafish
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Fibroblast Growth Factor 4
|
|
Concept
|
Fibroblast Growth Factor 8
|
|
Concept
|
Heart Transplantation
|
|
Concept
|
Axonemal Dyneins
|
|
Concept
|
Mice, 129 Strain
|
|
Concept
|
Blotting, Northern
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Retinal Cone Photoreceptor Cells
|
|
Concept
|
Stroke
|
|
Concept
|
Cardiac Myosins
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Macrophage Inflammatory Proteins
|
|
Concept
|
Body Patterning
|
|
Concept
|
Transcriptome
|
|
Concept
|
Upper Extremity Deformities, Congenital
|
|
Concept
|
Organogenesis
|
|
Concept
|
Gastrulation
|
|
Concept
|
Sumoylation
|
|
Concept
|
Calcium
|
|
Concept
|
Calcium-Binding Proteins
|
|
Concept
|
Brain Ischemia
|
|
Concept
|
Chromatin
|
|
Concept
|
Diagnosis, Differential
|
|
Concept
|
Electrophoresis, Agar Gel
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Heart Septal Defects
|
|
Concept
|
Hydrocephalus
|
|
Concept
|
Intercellular Junctions
|
|
Concept
|
Kinetics
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Salamandridae
|
|
Concept
|
Translocation, Genetic
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Computational Biology
|
|
Concept
|
Genomics
|
|
Concept
|
Potassium Channels, Voltage-Gated
|
|
Concept
|
Databases, Nucleic Acid
|
|
Concept
|
Sarcoplasmic Reticulum Calcium-Transporting ATPases
|
|
Concept
|
Cytoplasmic Dyneins
|
|
Academic Article
|
lin-12 and glp-1 are required zygotically for early embryonic cellular interactions and are regulated by maternal GLP-1 signaling in Caenorhabditis elegans.
|
|
Academic Article
|
Comparison of two murine models of familial hypertrophic cardiomyopathy.
|
|
Academic Article
|
Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene.
|
|
Academic Article
|
Cardiac electrophysiological phenotypes in postnatal expression of Nkx2.5 transgenic mice.
|
|
Academic Article
|
The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system.
|
|
Academic Article
|
Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome.
|
|
Academic Article
|
Repression of cell-cell fusion by components of the C. elegans vacuolar ATPase complex.
|
|
Academic Article
|
A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development.
|
|
Academic Article
|
Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia.
|
|
Academic Article
|
Characterization of sinoatrial node in four conduction system marker mice.
|
|
Academic Article
|
Complex genomic rearrangement in CCS-LacZ transgenic mice.
|
|
Academic Article
|
The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.
|
|
Academic Article
|
A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines.
|
|
Academic Article
|
Genome-wide identification of mouse congenital heart disease loci.
|
|
Academic Article
|
A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus.
|
|
Academic Article
|
Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.
|
|
Academic Article
|
Combinatorial specification of blastomere identity by glp-1-dependent cellular interactions in the nematode Caenorhabditis elegans.
|
|
Academic Article
|
TBX5 drives Scn5a expression to regulate cardiac conduction system function.
|
|
Academic Article
|
E2F3 plays an essential role in cardiac development and function.
|
|
Academic Article
|
Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]
|
|
Academic Article
|
Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease.
|
|
Academic Article
|
Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.
|
|
Academic Article
|
Ventricular fibrillation following autologous intramyocardial cell therapy for inherited cardiomyopathy.
|
|
Academic Article
|
sonic hedgehog is required in pulmonary endoderm for atrial septation.
|
|
Academic Article
|
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
|
|
Academic Article
|
Inducible recombination in the cardiac conduction system of minK: CreERT² BAC transgenic mice.
|
|
Academic Article
|
Configuration of DNA strands and mechanism of strand exchange in the Hin invertasome as revealed by analysis of recombinant knots.
|
|
Academic Article
|
Alignment of recombination sites in Hin-mediated site-specific DNA recombination.
|
|
Academic Article
|
The potential to differentiate epidermis is unequally distributed in the AB lineage during early embryonic development in C. elegans.
|
|
Academic Article
|
Hysteria in poliomyelitis.
|
|
Academic Article
|
Giant cell myocarditis in a 12-year-old girl with common variable immunodeficiency.
|
|
Academic Article
|
Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis.
|
|
Academic Article
|
Low-dose cyclosporin A therapy in children with refractory immune thrombocytopenic purpura.
|
|
Academic Article
|
Tetralogy of Fallot with congenital aortic valvar stenosis: the tetralogy-truncus interrelationship.
|
|
Academic Article
|
Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation.
|
|
Academic Article
|
MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus.
|
|
Academic Article
|
Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development.
|
|
Academic Article
|
A common genetic variant within SCN10A modulates cardiac SCN5A expression.
|
|
Academic Article
|
The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model.
|
|
Academic Article
|
De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects.
|
|
Academic Article
|
Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
|
|
Academic Article
|
TBX5: A Key Regulator of Heart Development.
|
|
Academic Article
|
Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation.
|
|
Academic Article
|
Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation.
|
|
Academic Article
|
Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm.
|
|
Academic Article
|
A promoter interaction map for cardiovascular disease genetics.
|
|
Academic Article
|
Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.
|
|
Academic Article
|
A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human.
|
|
Academic Article
|
Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics.
|
|
Academic Article
|
Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research.
|
|
Academic Article
|
Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development.
|
|
Academic Article
|
Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis.
|
|
Academic Article
|
Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types.
|
|
Academic Article
|
Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq.
|
|
Academic Article
|
Transcriptional Patterning of the Ventricular Cardiac Conduction System.
|
|
Academic Article
|
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
|
|
Academic Article
|
Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation.
|
|
Academic Article
|
Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation.
|
|
Academic Article
|
Chamber-specific transcriptional responses in atrial fibrillation.
|
|
Academic Article
|
Control of cardiomyocyte differentiation timing by intercellular signaling pathways.
|
|
Academic Article
|
Author Correction: Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome.
|
|
Academic Article
|
Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome.
|
|
Academic Article
|
Identification of direct transcriptional targets of NFATC2 that promote ß cell proliferation.
|
|
Academic Article
|
Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development.
|
|
Academic Article
|
Differential Etv2 threshold requirement for endothelial and erythropoietic development.
|
|
Academic Article
|
Detecting critical transition signals from single-cell transcriptomes to infer lineage-determining transcription factors.
|
|
Academic Article
|
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages.
|
|
Academic Article
|
Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization.
|
|
Concept
|
N-Myc Proto-Oncogene Protein
|
|
Concept
|
Smoothened Receptor
|
|
Concept
|
NAV1.5 Voltage-Gated Sodium Channel
|
|
Concept
|
NAV1.8 Voltage-Gated Sodium Channel
|
|
Concept
|
Filamins
|
|
Grant
|
Gene Regulatory Networks for Cardiac Morphogenesis
|
|
Grant
|
Genetic and Molecular Analysis of Congenital Heart Disease
|
|
Grant
|
Etiology of Congenital Heart Disease in Down Syndrome
|
|
Academic Article
|
ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment.
|
|
Academic Article
|
Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation.
|
|
Academic Article
|
An Anterior Second Heart Field Enhancer Regulates the Gene Regulatory Network of the Cardiac Outflow Tract.
|
|
Academic Article
|
A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.
|
|
Academic Article
|
Tbx5 maintains atrial identity in post-natal cardiomyocytes by regulating an atrial-specific enhancer network.
|